结构式
CAS: 89-86-1
分子式: C7H6O4
分子量: 154.12
中文名称: 2,4-二羟基苯甲酸
间苯二酚甲酸
对羟基水杨酸
雷琐酸
英文名称: 2,4-Dihydroxybenzoic acid
2,4-dihydroxy-Benzoic acid
beta.-Resorcylic acid
beta-resorcylic acid
性质描述: 白色针状结晶。从水中结晶时含有结晶水，在100℃时变成无水物。熔点218-219℃（急热的熔点213℃）。溶于热水、乙醇、乙醚。在水、酸或盐溶液中煮沸会脱去二氧化碳。与氯化铁作用呈红色。
质量标准：
外观 白色结晶粉末
含量 ≥ 99%
熔点 212-215℃
水分 ≤0.5%
用途: 2,4-二羟基苯甲酸兼有间苯二酚和水杨酸的化学性质，用于化学试剂比色测定铁、钛和其他元素、用于有机合成时，主要是作染料及药物中间体。2,4-二羟基苯甲酸在酸性媒介桃红3BM的生产中是一种主要的原料。
其它信息：
Product Identification
【Product Name】beta-Resorcylic acid
【Synonyms】2,4-DHBA 2,4-二羟基苯甲酸
【CAS】89-86-1
【Formula】C7H6O4
【Molecular Weight】154.12
【EINECS】201-946-9
【RTECS】VH3708050
【RTECS Class】Reproductive Effector
【Merck】12,8325
【Beilstein/Gmelin】1946213
【Beilstein Reference】4-10-00-01420
Physical and Chemical Properties
【Appearance】White to off-white crystalline powder.
【Solubility in water】Very soluble
【Melting Point】218-220℃
【Boiling Point】390℃
【Vapor Pressure】9E-7 (25℃)
【Density】1.54 g/cm3
【pKa/pKb】3.32 (pKa)
【Partition Coefficient】1.6
【Heat Of Vaporization】67.4 kJ/mol
【Heat Of Combustion】-2834 kJ/mol
【Usage】Intermediate for dyestuffs and drugs.
First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards Identification
【Ingestion】May cause irritation of the digestive tract.
【Inhalation】May cause respiratory tract irritation. May cause irritation of the mucous membranes.
【Skin】Causes skin irritation.
【Eyes】Causes eye irritation.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting Measures
【Flash Point】204℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Provide ventilation.
Stability and Reactivity
【Disposal Code】4
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents - strong bases.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Transport Information
【HS Code】2918 29 90
