质量标准:无色至淡黄色透明液体
纯度 ≥99%
水分 ≤0.5%
用途: 医药中间体。是合成头孢吡肟的关键原料,是制药工业的重要中间体。可作为良好溶剂。
其它信息:
Product Identification
【Product Name】1-Methylpyrrolidine 1-甲基吡咯烷,N-甲基吡咯烷
【Synonyms】N-Methyltetrahydropyrrole
【CAS】120-94-5
【Formula】C5H11N
【Molecular Weight】85.17
【EINECS】204-438-5
【RTECS】UY1420500
【RTECS Class】Other
【Beilstein/Gmelin】102445
【Beilstein Reference】5-20-01-00166
Physical and Chemical Properties
【Appearance】Colorless to light yellow liquid with an amine-like odor.
【Solubility in water】Miscible
【Melting Point】-76℃
【Boiling Point】80℃
【Vapor Pressure】99 (25℃)
【Density】0.7822 g/cm3 (15℃)
【pKa/pKb】3.45 (pKb)
【Partition Coefficient】.76
【Heat Of Vaporization】32.3 kJ/mol
【Vapor Density】2.9
【Refractive Index】1.4236 (20℃)
First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Hazards Identification
【Inhalation】Causes respiratory tract irritation. Vapors may cause dizziness or suffocation.
【Skin】Causes skin irritation.
【Eyes】Causes eye irritation.
【Ingestion】Causes digestive tract irritation.
【Hazards】Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
【UN (DOT)】1993
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】The toxological properties of this substance have not been fully investigated.
【Poison Class】2
Fire Fighting Measures
【Flash Point】-22℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Extremely flammable liquid. Containers may explode in the heat of a fire. Will be easily ignited by heat, sparks or flame. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
【Upper exp. limit】9.5
【Fire Potential】HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Stability and Reactivity
【Incompatibilities】
Oxidizing agents
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
【UN Number】1993
【Hazard Class】3
【Packing Group】I; II; III