网站首页企业介绍  |  企业荣誉  |  产品订货  |  产品中心  |  企业采购  |   联系方式  |  


名称:2,4-二氟苯胺
 

纯度:99% 包装:250公斤/桶
结构式
    

CAS:  367-25-9
分子式:  C6H5F2N
分子量:  129.11

中文名称:  2,4-二氟苯胺 

英文名称:  2,4-Difluoroaniline
                 2,4-difluoro-anilin
                 2,4-difluorobenzenamine
                 2,4-difluoro-benzenamin 

性质描述:  无色或淡黄色透明液体,遇光后呈棕色。凝固点-7.5~-7℃,沸程169-171℃,相对密度1.20-1.27,折射率1.5063,闪点62℃。不溶于水,易溶于乙醇和乙醚。

用途:  有机合成的中间体。医药上用于二氟苯水杨酸和多氟啶酸的合成。

  氟苯水杨酸是羧酸类非甾抗炎药,国际非专有药名(INN)为Diflunisal。这个水杨酸的新衍生物结构中不含有阿司匹林的乙酰基而含有二氟苯基,所以抗血小板的副作用小,且胃肠道反应轻微,作用时间可维持8-12h,可能是水杨酸类药物中最有发展前途的品种。

  2,4-二氟苯胺也是农药的重要中间体。

其它信息:

Product Identification
【Product Name】2,4-Difluorophenylamine
【Synonyms】 2,4-二氟苯胺
【CAS】367-25-9
【Formula】C6H5F2N
【Molecular Weight】129.11000000000001
【EINECS】206-687-5
【RTECS】BX3680000
【RTECS Class】Mutagen
【Merck】13,3171
【Beilstein/Gmelin】2802556
【Beilstein Reference】4-12-00-01112

Physical and Chemical Properties
【Appearance】Dark reddish-purple liquid.
【Solubility in water】20 g/L
【Melting Point】-7℃
【Boiling Point】170℃
【Vapor Pressure】1.6 (25℃)
【Density】1.268 g/cm3 (20℃)
【pKa/pKb】10.74 (pKb)
【Partition Coefficient】1.54
【Heat Of Vaporization】40.5 kJ/mol
【Usage】Substance is used in organic syntheses.
【Vapor Density】4.45
【Refractive Index】1.5043 (20℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Aspiration may lead to pulmonary edema. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia. Inhalation at high concentrations may cause CNS depression and asphixiation.
【Skin】May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause irritation and dermatitis. May cause cyanosis of the extremities.
【Eyes】May cause eye irritation. May cause chemical conjunctivitis and corneal damage.
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. Overexposure may cause methemoglobinemia.
【Hazards】When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
【EC Risk Phrase】R 20/21/22 36/38
【EC Safety Phrase】S 26 36/37/39
【UN (DOT)】2941

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. Repeated exposure may cause sensitization dermatitis.

Fire Fighting Measures
【Flash Point】62℃
【Autoignition】>600℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire.
【Fire Potential】This compound is combustible.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity
【Disposal Code】2
【Incompatibilities】Oxidizing agents
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】2941
【Hazard Class】6.1
【Packing Group】III
【HS Code】2921 42 10



选购说明:

1、欢迎选购本公司产品,拨打电话后,我们会为您送货上门,并提供满意的销售服务。

2、本公司2,4-二氟苯胺价格实惠,质量可靠,出库时可提供质检报告和2,4-二氟苯胺厂家说明书等资料。