结构式
CAS: 6443-72-7
分子式: C11H12O4
分子量: 208.22
中文名称: 3,4-二甲氧基肉桂酸
英文名称: 3,4-dimethoxycinnamonitrile
3-(3,4-dimethoxyphenyl)acrylonitrile
性质描述: 淡黄色结晶粉末，熔点183-187℃。 不溶于水，溶于乙醇，乙酸乙酯等有机溶剂。
质量标准
外观 白色结晶性粉末
灼烧残渣 ≤0.1%
干燥失重 ≤0.5%
熔点 175-182℃
含量 ≥98.5%
用途:一种有机合成中间体。
其它信息：
Product Identification
【Product Name】3-(3,4-Dimethoxyphenyl)acrylonitrile
【Synonyms】3,4-二甲氧基肉桂酸
【CAS】6443-72-7
【Formula】C11H11NO2
【Molecular Weight】189.21
【EINECS】229-240-6
【Beilstein/Gmelin】2212894
【Beilstein Reference】4-10-00-01786
Physical and Chemical Properties
【Appearance】Clear yellow crystalline powder.
【Melting Point】96
【Boiling Point】317
【Partition Coefficient】2.16
First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards Identification
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May be metabolized to cyanide which in turns act by inhibiting cytochrome oxidase impairing cellular respiration.
【Skin】May cause skin irritation. May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration.
【Eyes】May cause eye irritation.
【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Metabolism may release cyanide, which may result in headache, dizziness, weakness, collapse, unconsciousness and possible death.
【Hazards】Contact with metals may evolve flammable hydrogen gas.
【UN (DOT)】2811
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration.
Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Do NOT get water inside containers. Cool containers with flooding quantities of water until well after fire is out.
【Fire Potential】Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Incompatibilities】Strong acids, strong bases, strong oxidizing agents.
【Decomposition】Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
【UN Number】2811
【Hazard Class】6.1
【Packing Group】I; II; III
