结构式
CAS: 15206-55-0
分子式: C9H8O3
分子量: 164.16
中文名称: α-氧代苯乙酸甲酯
A-氧代苯乙酸甲酯
苯乙酮酸甲酯
苯甲酰甲酸甲酯
英文名称: alpha-oxo-benzeneacetic acid methyl ester
methyl benzoylformate
Methyl phenylglyoxylate
Phenylglyoxylic acid methyl ester
性质描述: 低温下为淡黄色固体，18℃以上时为淡黄色液体，沸点为246-248℃，相对密度1.155，折光率1.5268。
制备方法
方法一：其制备方法是在反应瓶中加入氯化钠和硫酸，室温下搅拌，滴加苯甲酰腈，控制温度在30℃左右，滴加完后保温3 h，再滴加甲醇，升温回流5 h，反应结束后减压除去甲醇得成品。
方法二：由苯甲酰酸与甲醇经酯化反应则制得。将环甲醇和苯甲酰甲酸加入反应锅内，搅拌下缓缓加入硫酸。加热回流12h后，回收过量甲醇。酯化物用稀碳酸钠溶液中和，分取油层，水层用苯提取。提取液与油层合并，经无水硫酸钠干燥后，进行蒸馏，先回收溶剂苯，再减压蒸出低沸物，然后收集137-146℃（2.4kPa）馏分，取为苯甲酰甲酸甲酯。所用原料苯甲酰甲酸是由苯乙烯氧化得到的（见04960），苯甲酰甲酸计，酯化收率为50%以上。
用途
1.UV固化型涂料和油墨。
2.苯甲酰甲酸甲酯是除草剂苯嗪草酮的中间体。
3.用于有机合成。
其它信息：
Product Identification
【Product Name】Methyl phenylglyoxylate
【Synonyms】苯甲酰甲酸甲酯
【CAS】15206-55-0
【Formula】C9H8O3
【Molecular Weight】164.16
【EINECS】239-263-3
【Beilstein/Gmelin】1100868
【Beilstein Reference】4-10-00-02738
Physical and Chemical Properties
【Appearance】Clear slightly yellow.
【Solubility in water】Insoluble
【Melting Point】16℃
【Boiling Point】248℃
【Vapor Pressure】7.5 (20℃)
【Density】1.1561 g/cm3 (20℃)
【Refractive Index】1.5291 (20℃)
First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】The toxicological properties of this material have not been investigated.
Fire Fighting Measures
【Flash Point】77
【Autoignition】> 500
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.
Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment.
Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Irritating and toxic fumes and gases.
Transport Information
【HS Code】2918 30 00
