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名称:对羟基苯乙腈
 

纯度:≥99.0 % 包装:20公斤/桶
结构式
                

CAS:  14191-95-8
分子式:  C8H7NO
分子量:  133.1494

中文名称:  4-羟基苯乙腈
                   对羟基苯乙腈

英文名称:  4-Hydroxyphenylacetonitrile
                   p-hydroxybenzyl cyanide
                   p-hydroxyphenylacetonitrile
                   p-Hydroxybenzylcyanide

性质描述:  类白色结晶体,熔点68-72,沸点330 ,闪点178,微溶于水。

质量标准:
含量  99.0%
熔点  68-72℃
水分  <0.2%


用途:  有机合成中间体,用作合成氨酰心安药物的中间体。

其它信息:

Product Identification
【Product Name】4-Hydroxybenzyl cyanide;对羟基苯乙腈
【Synonyms】p-Hydroxyphenylacetonitrile
【CAS】14191-95-8
【Formula】C8H7NO
【Molecular Weight】133.15
【EINECS】238-046-0
【RTECS】AM0530000
【RTECS Class】Mutagen
【Beilstein/Gmelin】1934470
【Beilstein Reference】4-10-00-00554
【EC Class】harmful

Physical and Chemical Properties
【Appearance】Yellow solid.
【Solubility in water】Slightly soluble
【Melting Point】68-71℃
【Boiling Point】330℃

First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Store in a cool, dry place. Store in a tightly closed container.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.

Hazards Identification
【Ingestion】May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause cardiac disturbances. May cause tissue anoxia, characterized by weakness, headache, dizziness, confusion, cyanosis, weak and irregular heart beat, collapse, unconsciousness, convulsions, coma and death. May cause central nervous system effects.
【Inhalation】May cause respiratory tract irritation. May cause effects similar to those described for ingestion.
【Skin】May be absorbed through the skin in harmful amounts. No information regarding skin irritation and other potential effects was found.
【Eyes】May cause eye irritation.
【EC Risk Phrase】R 20/21/22 36/37/38
【EC Safety Phrase】S 26 36/37/39
【UN (DOT)】3276

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Poison Class】1 (Extremely strong toxins)

Fire Fighting Measures
【Flash Point】178℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
【Fire Potential】Non-Combustible

Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity
【Disposal Code】6
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
【Decomposition】Nitrogen oxides, carbon monoxide, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】3276
【Hazard Class】6.1
【Packing Group】I; II; III
【HS Code】2926 90 95



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