结构式
CAS: 321-14-2
分子式: C7H5ClO3
分子量: 172.57
中文名称: 5-氯水杨酸
5-氯-2-羟基苯甲酸
5-氯代水杨酸
2-羟基-5-氯苯甲酸
英文名称: 5-chloro-2-hydroxy-Benzoic acid
5-Chlorosalicylic acid
5-chloro-salicylic acid
性质描述: 白色结晶性粉末。熔点173-174℃（172℃，174-176℃）。溶于热水，难溶于冷水，易溶于乙醇、乙醚、苯、氯仿和乙酸。5-氯水杨酸与氯化铁作用呈红紫色。
质量指标：
外观 白色结晶粉末
含量 ≥99.50%
熔点 172~176℃
水分 ≤0.5%
灼烧残渣 ≤0.15%
3-氯水杨酸 ≤0.40%
3,5-二氯水杨酸 ≤0.40%
用途: 染料、医药的中间体。
其它信息：
Product Identification
【Product Name】5-Chloro-2-hydroxybenzoic acid 5-氯水杨酸
【Synonyms】2-Hydroxy-5-chlorobenzoic acid
【CAS】321-14-2
【Formula】C7H5ClO3
【Molecular Weight】172.57
【EINECS】206-283-9
【RTECS】VO2080000
【RTECS Class】Drug
【Beilstein/Gmelin】2046665
【Beilstein Reference】4-10-00-00207
【EC Class】harmful
Physical and Chemical Properties
【Appearance】Cream crystalline powder.
【Solubility in water】Very soluble
【Melting Point】171 - 175
【Boiling Point】321
【pKa/pKb】2.64 (pKa)
【Partition Coefficient】1.76
First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Wash mouth out with water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Store in a cool, dry place. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards Identification
【Ingestion】Harmful if swallowed. Causes digestive tract irritation.
【Inhalation】May cause respiratory tract irritation.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【EC Risk Phrase】R 22 36/37/38
【EC Safety Phrase】S 26 36/37/39
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Poison Class】3
Fire Fighting Measures
【Autoignition】> 500
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
【Disposal Code】4
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, chlorine.
Transport Information
【HS Code】2918 29 90
